Honeywell HUL520B - Manuals

Page 3 - earlier findings

Taken together, our findings show that VHP treatment exhibits the best combination of rapid inactivation 36 of SARS-CoV-2 and preservation of N95 respirator integrity, under the experimental conditions used here 37 (Figure 1C). UV radiation kills the virus more slowly and preserves comparable respir...

Page 4 - TCID

54 55 Figure 1. Decontamination of SARS-CoV-2 by four different methods. A) SARS-CoV-2 on N95 fabric 56 and stainless steel surface was exposed to UV, 70 ºC dry heat, 70% ethanol and vaporized hydrogen 57 peroxide (VHP). 50 µ l of 10 5 TCID 50 /mL of SARS-CoV was applied on N95 and stainless steel (...

Page 5 - References

of the slope, and intercept, i.e. initial virus titer). Black dashed line shows maximum likelihood estimate 65 titer at the Limit of Detection (LOD) of the assay: 10 0.5 TCID 50 /mL media. B) Mask integrity. 66 Quantitative fit testing results for all the decontamination methods after decontaminatio...

Page 7 - Supplemental methods; Laboratory experiments

Supplemental methods 101 Short literature review: 102 The COVID-19 pandemic has highlighted the necessity for large-scale decontamination procedures for 103 PPE, in particular N95 respirator masks 1 . SARS-CoV-2 has frequently been detected on PPE of 104 healthcare workers 2 . The environmental stab...

Page 12 - Regression prior distributions

We use the direct-from-well data likelihood function described above, except that now instead of 222 estimating titer distribution about a shared mean µ ij we estimate λ i under the assumptions that our 223 observed well data Y ijkdl reflect the titers v ij (t). 224 Regression prior distributions 22...

Page 13 - the fit factor; to the equivalent observed filtration rate Y

2, and 3 decontamination cycles. We label the control treatment i = 0. So we denote by F ijk the fit factor 243 for the j th mask from the i th treatment after k decontaminations (with k = 0 for the initial value). 244 We first converted fit factors F ijk to the equivalent observed filtration rate Y...

Page 14 - Observation model and likelihood function; Decay model

Observation model and likelihood function 247 We modeled the censored observation process as follows. logit(Y ijk ) values are observed with 248 Gaussian error about the true filtration logit(p ijk ), with an unknown standard deviation σ o , and then 249 converted to fit factors, which are then cens...

Page 16 - σ in the; to one of two

We placed weakly informative Half-Normal priors on the logit-space standard deviations σ p , σ ε , and 287 σ o . σ p reflects variation in individual masks’ initial filtration about p avg . σ ε reflects variation in mask’s true 288 degree of degradation between decontaminations about the expected de...

Page 17 - Supplemental table; Steel; Code and data availability; archived online at OSF: and available on Github:; Acknowledgements

303 304 305 306 Supplemental table 307 Table S1. Effect of decontamination method on SARS-CoV-2 viability and N95 mask integrity. 308 half-life (min) time to one thousandth (min) time to one millionth (min) Treatment Material median 2.5% 97.5% median 2.5% 97.5% median 2.5% 97.5% Control N95 mask 78 ...

Page 18 - Supplemental references; Decontamination and Reuse of Filtering Facepiece Respirators

We would like to thank Madison Hebner, Julia Port, Kimberly Meade-White, Irene Offei Owusu, 314 Victoria Avanzato and Lizzette Perez-Perez for excellent technical assistance. This research was 315 supported by the Intramural Research Program of the National Institute of Allergy and Infectious 316 Di...

Page 19 - at

11. Viscusi DJ, Bergman MS, Eimer BC, Shaffer RE. Evaluation of five decontamination methods for 351 filtering facepiece respirators. Ann Occup Hyg 2009;53:815-27. 352 12. Avilash Cramer ET, Sherryl H Yu, Mitchell Galanek, Edward Lamere, Ju Li, Rajiv Gupta, Michael 353 P Short. disposable N95 masks ...

Honeywell HUL520B - Manuals

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